The possibility of a new global socio-cultural integration in a situation of dominance of deglobalization processes is substantiated. Deglobalization is considered as a natural consequence of Western globalism based on the technogenic-consumer civilizational model of development. The features of deglobalization in the economic, political, social and cultural spheres are fixed. The idea of the need to search for new forms of uniting the world community on other ideological grounds and principles is defended. Such foundations and principles are found in the basic categories of Russian culture: peace, sobornost, brotherhood, non-possessiveness. Using the example of Siberia, the historical practice of cooperation between peoples is analyzed, where the indicated principles have already been partially implemented. The authors summarize the experience of regional cross–border cooperation within the framework of the activities of the International Coordinating Council “Our Common Home - Altai”, which unites state and public structures of the border regions of Russia, Mongolia, Kazakhstan and China. This experience is considered as a possible guideline for the future of a new unification of mankind.